Employment Grade and Coronary Heart Disease in British Civil Servants
The first Whitehall Study: a longitudinal cohort of 17,530 male civil servants followed for seven and a half years, showing a clear inverse relationship between employment grade and coronary heart disease mortality — messengers dying at 3.6 times the rate of administrators. Crucially, the gradient persisted after adjusting for all established coronary risk factors (smoking, blood pressure, cholesterol, obesity, physical activity), implying that rank itself — not just the behaviours associated with it — shapes health. This paper is the foundational empirical evidence for the social determinants of health, and for understanding control, status, and voice as biological as well as organisational phenomena.
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